Year 2020 
Journal Info. Nanoscale, 12, 21560 (2020) 
Author Hao Chen, Anupam Das, Liyan Bi, Namhyun Choi, Joung-Il Moon, Yixuan Wu, Sohyun Park and Jaebum Choo* 
etc. Invited Review 

Abstract

This minireview reports the recent advances in surface-enhanced Raman scattering (SERS)-based assay devices for the diagnosis of infectious diseases. SERS-based detection methods have shown promise in overcoming the low sensitivity and multiplex detection problems inherent to fluorescence detection. Therefore, it is interesting to investigate the current status, challenges, and applications associated with SERS-based microdevices for the point-of-care (POC) diagnosis of infectious diseases. The majority of this review highlights three different types of microdevices, namely microfluidic channels, lateral flow assay strips, and three-dimensional nanostructured substrates. Furthermore, the integration of portable Raman spectrophotometry with microdevices provides an ideal platform for the diagnosis of various infectious diseases in the field. Integrated SERS-based assay systems also enable measurements in minimal sample volumes and at low analyte concentrations of viral or bacterial samples. A significant number of studies using the SERS-based assay system have been performed recently to realize POC diagnostics, especially under resource-limited conditions. This portable SERS sensor is expected to be a nextgeneration POC assay system that could overcome the limitations of current fluorescence-based assay systems. This minireview summarizes recent advances in the development of SERS-based microdevices for the diagnosis of infectious diseases. Lastly, challenges to overcome and future perspectives are discussed.

Year Title Journal Info. etc.
2020  Recent advances in surface-enhanced Raman scattering-based microdevices for point-of-care diagnosis of viruses and bacteria file Nanoscale, 12, 21560 (2020)  Invited Review 
2020  SERS imaging-based aptasensor for ultrasensitive and reproducible detection of influenza virus A file Biosensors & Bioelectronics, 167, 112496 (2020)   
2020  SERS-active Au@Ag core-shell nanorod (Au@AgNR) tags for ultrasensitive bacteria detection and antibiotic-susceptibility testing file Talanta, 220, 121397 (2020)   
2020  Improvement of reproducibility and thermal stability of surface-enhanced Raman scattering-based lateral flow assay strips using silica-encapsulated gold nanoparticles file Sensors & Actuators: B. Chemical, 321, 128521 (2020)   
2020  SERS biosensors for ultrasensitive detection of multiple biomarkers expressed in cancer cells file Biosensors & Bioelectronics, 164, 112326 (2020)   
2020  Integrated hand-powered centrifugation and paper-based diagnosis with blood-in/answer-out capabilities file Biosensors & Bioelectronics, 165, 112282 (2020)   
2020  Multi-emitting fluorescence sensor of MnO2-OPD-QDs for the multiplexed and visual detection of ascorbic acid and alkaline phosphatase file Journal of Materials Chemistry C, 8, 5554-5561 (2020)   
2020  Analysis of deoxyribonuclease activity by conjugation-free fluorescence polarization in sub-nanoliter droplets file Analyst, 145, 3222-3228 (2020)  Cover page 
2020  Present and Future of Surface-Enhanced Raman Scattering file ACS Nano, 14, 28-117 (2020)   
2020  Performance Evaluation of Surface-Enhanced Raman Scattering−Polymerase Chain Reaction Sensors for Future Use in Sensitive Genetic Assays file Analytical Chemistry, 92, 2628-2634 (2020)   
2020  Ratiometric fluorescence and colorimetry dual-mode assay based on manganese dioxide nanosheets for visual detection of alkaline phosphatase activity file Sensors & Actuators: B. Chemical, 302, 127176 (2020)   
2019  SERS-based immunoassay using gold-patterned array chips for rapid and sensitive detection of dual cardiac biomarkers file Analyst, 144, 6533-6540 (2019)  Cover page 
2019  SERS-based Immunoassays for the Detection of Botulinum Toxins A and B Using Magnetic Beads file Sensors, 19, 4081 (2019)   
2019  Epitaxially aligned submillimeter-scale silver nanoplates grown by simple vapor transport file Nanoscale, 11, 17436-17443 (2019)   
2019  Quantitative Serodiagnosis of Scrub Typhus Using SERS-Based Lateral Flow Assay Platforms file Analytical Chemistry, 91, 12275-12282 (2019)  Cover page 
2019  Gold nanorods functionalized by a glutathione response near-infrared fluorescent probe as a promising nanoplatform for fluorescence imaging guided precision therapy file Nanoscale, 11, 12220-12229 (2019)   
2019  A Facile Low-Cost Paper-based SERS Substrate for Label-free Molecular Detection file Sensors & Actuators B, 291, 369-377 (2019)   
2019  Detection of hypochlorous acid fluctuation via a selective near-infrared fluorescent probe in living cells and in vivo under hypoxia stress file Journal of Materials Chemistry B, 7, 2557-2564 (2019)   
2019  Modification of Phage Display Technique for Improved Screening of High-Affinity Binding Peptides Journal of Biotechnology file Journal of Biotechnology, 289, 88-92 (2019)   
2019  High-throughput Microfluidic Imaging Flow Cytometry file Current Opinion in Biotechnology, 55, 36-43 (2019)